The primary goal of the profession of pharmacy is to improve public health through ensuring the safe and effective use of medications. For instance, those that have taken the Pharmacy Technician Certification exam understand that a substantial part of the exam is made up of questions that target medication order entry and the prescription filling process. This includes assessments of the candidate's ability to calculate individual drug doses and accurately convert between units of measurement. Thus, it is important for pharmacy technicians to have a fundamental understanding of everyday math problems that are commonly encountered in pharmacy practice. In the Pharmacy Calculations for Pharmacy Technicians: Units of Measurement and Methods of Calculation continuing education activity, the focal points included solving pharmacy math problems using dimensional analysis and ratio-proportion methods of calculation, converting between units of measurement, and determining the day's supply of medications.
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Alligation is one of the simple and illustrative methods in pharmacy to calculate the proportion of any two solutions to be mixed to prepare final solution of required concetration. It is highly useful for the pharmacy technicians to quickly estimate alligation ratio and then to prepare solutions of desired concentration from available stock solutions.
Is this method different from dilution? Yes,of course, but not completely different. When water is used as one of the solvent alligation simply becomes a dilution technique. In all other cases, alligation plays unique role in pharmacy calculations. So let's go in detail here.
Dilution vs alligation in pharmacy Dilution is a simple method for preparing a lower concentration from a solution of higher concentration. Suppose you have a concetrated solution of 12M and you want to prepare 60 ml of 8M solution from the concetrated solution.
Now you can simply dilute it with water by using the following formula. So by using above equation, you can mix take 40 ml of concetrated solution and mix it with 20 ml of water to produce 60 ml of final solution.
This is an easy task as we are simply using water as the second concetration. On the other hand, many of the times we require an intermediate concentration from two different concentrations where alligation plays its role in pharmacy.
The solutions should be mixed at a specific proportion in order to get required concentration. This can't be calculated by simple dilution forumula as we are not using water to dilute the sample. Here alligation mathematics comes into the play to solve the problem. The proportion of two solution that should be mixed can be calculated as alligation ratio. You can find few calculators available on the internet which simply gives you the output of alligation ratio and volumes.
Here is such an online alligation calculator that may found useful. Now we will go with few of the working examples on this method and different steps required for its calculation.
How many grams of 1. Therefore 1 part of 1. Since final weight of ointment is 15 g,the weight of the 1. Hence 5g of 1. Since the diluting solution is not given it can be considered as water. Here we can clearly observe that all concentration terms are not expressed equal.
Please share this article, if you like. Working example 2: How many grams of 1. Step 1: Identify the data given. Higher concentration sp. Share :. Follow us. Join with us Get the latest updates and posts Follow us at.