ABBOTT REALTIME HBV PDF

By coupling high sensitivity with a large dynamic range, the Abbott RealTime HBV assay is useful in monitoring the response to antiviral therapy. Hepatitis B virus HBV is a small partially double-stranded virus belonging to the family of the Hepadnaviridae that can cause acute or chronic hepatitis 2. Millions of people around the world are infected by HBV, and it is estimated that about million people worldwide have developed a persistent infection 6. Measurement of HBV levels in serum is a reliable marker for prognosis of acute and chronic infection and plays an important role in the management of patients receiving antiviral drugs 7 , 8. Monitoring of HBV DNA allows to predict the success of antiviral therapy and to identify the development of drug resistance. Real-time PCR is a new molecular tool that is progressively replacing endpoint PCR systems for monitoring patients with chronic hepatitis B since it allows for high sensitivity, a broad dynamic range, accuracy, and rapid results 1 , 9.

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Class 3 Device Recall Abbott RealTime HBV Assay

For more information, contact Abbott. Links which take you out of Abbott worldwide websites are not under the control of Abbott, and Abbott is not responsible for the contents of any such site or any further links from such site. Abbott is providing these links to you only as a convenience, and the inclusion of any link does not imply endorsement of the linked site by Abbott. The website that you have requested also may not be optimised for your screen size. Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions. Product Description.

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For more information, contact Abbott. The assay is intended for use as an aid in the management of patients with chronic HBV infection undergoing anti-viral therapy. The assay can be used to measure HBV DNA levels at baseline and during treatment to aid in assessing response to treatment. The results from the Abbott RealTi m e HBV assay must be interpreted within the context of all relevant clinical and laboratory findings. Assay performance for determining the clinical stage of HBV infection has not been established. Clinical performance characteristics have been established for individuals treated with adefovir dipivoxil. This assay is not intended for use as a screening test in blood or blood products for HBV or as a diagnostic test to confirm the presence of HBV infection.

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Conceived and designed the experiments: M-L. Performed the experiments: M-L. Analyzed the data: M-L. Contributed to the writing of the manuscript: M-L. The authors confirm that all data underlying the findings are fully available without restriction. All data are included within the paper. Selection of drug-resistant strains may lead to failure of HBV antiviral therapy.

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