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The authors report a single-institute study of 90 cases of IFG, which is the largest study until now. Data were obtained from the medical records and the pathology, microbiology, and radiology departments.
All relevant clinical data, imaging characteristics, surgical procedure performed, perioperative findings, and follow-up data were recorded from the case files. Telephonic follow-up was also performed for a few patients to find out their current status.
The mean patient age was Headache 54 patients was the most common presenting complaint, followed by visual symptoms 35 patients , fever 21 patients , and others such as limb weakness 13 patients or seizure 9 patients. Cranial nerve involvement was the most common sign 47 patients , followed by motor deficit 22 patients and papilledema 7 patients.
The mean duration of symptoms before presentation was 6. Thirty patients A pure intracranial location of the IFG was seen in 49 cases Open surgery, that is, craniotomy and decompression, was performed in 55 cases, endoscopic biopsy was done in 30 cases, and stereotactic biopsy was performed in 5 cases.
Aspergilloma 43 patients was the most common fungal mass, followed by zygomycosis 13 patients , chromomycosis 9 patients , cryptococcoma 7 patients , mucormycosis 5 patients , and candida infection 1 patient. In 12 cases, the exact fungal phenotype could not be identified. The mean duration of the follow-up was The mortality rate was Early diagnosis, aggressive surgical decompression, and a course of promptly initiated antifungal therapy are associated with a better prognosis.
Based on 1 article published since Why 1 article? Copyright C by Expertscape Inc.. Intracranial fungal granuloma: a single-institute study of 90 cases over 18 years.
Devi Bhagavatula Indira
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Laxmi Devi Bhagavatula
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Indira Devi Bhagavatula