Introduction: due to the significant increase in the obesity rate in recent years, public health has been facing in many countries of the world, one of the major problems caused by this disease. Because of this, natural products arise, herbal, to assist in the treatment of obesity due to their safer effects. Among these, stands out the extract obtained from dried fruits of Garcinia Cambogia GC , which has been studied and used as a natural supplement for weight loss. Objective: to investigate the GC administration as a coadjuvant factor in the treatment of obesity regarding to its effectiveness, way of action, recommended daily amount, side effects and contraindications, as a way of food and nutritional security for the population. Methodology: literature review.
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Hydroxycitric acid HCA is a derivative of citric acid that is found in a variety of tropical plants including Garcinia cambogia and Hibiscus subdariffa. The - -hydroxycitric acid isomer is the one found in Garcinia. Laboratory and animal studies of HCA have produced results that indicate a potential for modulation of lipid metabolism. One isomer of HCA, known as 2 S ,3 R -HCA, inhibits pancreatic alpha-amylase and intestinal alpha-glucosidase , leading to a reduction in carbohydrate metabolism in vitro. Researchers at the University of Houston reported hydroxycitrate is capable of dissolving calcium oxalate crystals, a component of human kidney stones. Recent studies shows kidney stones are layered and the stones may form and dissolve with time.
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